Things You Should Know Before Taking Fluoxetine

hydrochloride is an antidepressant drug used medically in the treatment of , obsessive-compulsive , bulimia nervosa, premenstrual dysphoric and panic .

Fluoxetine is also used to treat many other conditions, such as ADHD. It is sold under the brand names Prozac, Symbyax, Sarafem, FLUX, Fontex, Foxetin, Ladose, Fluctin, Prodep, Fludac, Oxetin and Lovan. Fluoxetine was derived from diphenhydramine, an antihistamine found to inhibit reuptake of the neurotransmitter serotonin.

Compared to other popular selective serotonin reuptake inhibitors (), fluoxetine has a strong energizing effect. This makes fluoxetine highly effective in treatment of clinical depression cases where symptoms like depressed mood and lack of energy prevail. Although stimulating, it is also approved for a variety of anxiety disorders, including panic disorder and obsessive compulsive disorder.

Prozac was approved by the FDA on December 29, 1987 and introduced in the US at the beginning of 1988. The drug became very popular, with millions around the world having taken the medication. In the fall of 2001, Eli Lilly lost a patent dispute with Barr Laboratories and now fluoxetine hydrochloride is manufactured by many companies. Prozac’s popularity and selling success has been aided greatly by Lilly’s extensive marketing campaign for the drug, considered one of the most successful in the history of American pharmaceuticals.

Fluoxetine hydrochloride is approved in the United States to treat depression, obsessive-compulsive disorder, bulimia nervosa, premenstrual dysphoric disorder and panic disorder. In the United Kingdom, it is approved to treat depression with or without anxiety, bulimia nervosa, and obsessive-compulsive disorder.

In December 2003 the FDA approved Symbyax to treat bipolar depression. Symbyax is a combination of fluoxetine and olanzapine. (However, the pure form of fluoxetine can cause mania, mixed-states, rapid cycling and psychosis in bipolar patients, particularly if the patient is not also taking a mood stabilizer.)

Common adverse effects include anxiety, which is possibly associated with an interaction of fluoxetine with the pineal gland, in addition to restlessness and insomnia. Weight loss, trembling, weakness, skin rash, anorgasmia, itching, and a decrease in sexual drive, have also been reported. Finally it has been reported to cause subsequent weight gain.

Like other SSRIs, an overdose of fluoxetine or combining it with other antidepressants can lead to serotonin syndrome.

Fluoxetine is eliminated very slowly by the body. The half-life of fluoxetine after a single dose is two days and, after multiple dosing, four days. The liver then metabolizes fluoxetine into norfluoxetine, a desmethyl metabolite, which is also a serotonin reuptake inhibitor; norfluoxetine has an even longer half-life, i.e. 8.6 and 9.3 days for single and repeated dosage respectively. These long half-lives may be helpful in those patients with compliance issues, but fluoxetine is most effective when taken daily. Other SSRIs have, by comparison, a very short half-life.

Some professionals feel that it is fluoxetine’s long half-life that gives it much of its therapeutic utility, however this has never been proven under rigorous scientific study. Nevertheless, its long half life is also relevant because suddenly discontinuing SSRIs is known to produce both somatic and psychological withdrawal symptoms, a phenomenon known as “SSRI discontinuation syndrome”. It is generally accepted that fluoxetines withdrawal symptoms are much smoother than with other SSRIs, as the substance takes several days to completely leave the system. Fluoxetine is a potent CYP2D6 inhibitor, which can decrease metabolism of other medications.

The information presented here should not be interpreted as advice. Please consult with your physician before taking this or any other drug.

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Basil More Than A Kitchen Plant

A universally known fact is that aromatherapy uses essential extracted from plants. One of the most commonly used essential oil in aromatherapy is that of . got its name from the Greek word basileum meaning king. Considered as “king among plants” as it was one of the ingredients on the list of blended to massage kings.

Basil is an important as its uses are two-fold, for cooking as well as to cure a variety of ailments. The covers and offers a plethora of benefits. If added early while cooking, it loses its ; hence it should be used as soon as it is plucked from the plant. It ought be added towards the end of cooking. It exudes a warm, gentle unique and fragrance in cooking.

The leaves of basil are steam-distilled to create oil. Medically, it provides relief to sore gums, ulcers, chest infections and digestive problems. It has been used as a brain stimulant and an antispasmodic, making it wonderful in the treatment of bronchitis and whooping cough.

Basil is said to have uplifting and refreshing properties. 2-3 drops of basil oil is known to relieve mental fatigue, tension, stress, mild anxiety, loss of appetite, flatulence, nausea, sinusitis, cold, fever, earaches, eases rheumatic, arthritic and muscular pains.

A potpourri of dried basil leaves and flowers creates a fragrant atmosphere wherever kept. It is also used as an insect repellent, as burned sprigs of basil drive away mosquitoes. If you keep a potted plant of basil on the windowsill, it will deter flies from entering your home.

Basil oil, when mixed with massage oil and gently rubbed over the stomach, helps to ease many types of digestive problems. Basil should be used sparingly on skin as it could cause irritation. If you want to add a few drops to your bath, dilute it with a carrier oil, or mix it with a skin cream or lotion.

It should NOT be used during pregnancy. Basil helps with , increases alertness, aids in concentration, relieves headaches, head congestion and migraines. Basil regulates the menstrual cycle and reduces menstrual cramps. The herb blends well with rosemary, lavender, bergamot, clary sage, geranium and citrus oils.

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Serious Heart Attacks

are a very serious condition that ‘attack’ suddenly. They can be characterized by a spectrum of chest pains and discomfort as well as sweating, vomiting and nausia. Sometimes these symptoms can even result in a complete loss of consciousness. attacks occur when the supply to a part of the heart is interrupted. This interuption causes both death and scarring of the tissue in the local area of the heart.

Due to the fact that the interuption can vary in size, as can the area that is affected. Large or small, heart attacks are serious and often life-threatening. Deemed as such they are a emergency which needs immediate attention from an emergency service. Staying on top of heart attack symptoms as well as the combination of complete history, blood tests and ECG findings are what make up the diagnosis for heart attacks.

In recovery the most important thing is restoring the flow of blood back to the area of the heart that has been interrupted. This is acheived through thrombolysis and/or angioplasty. Thrombolysis is a in which the clot is dissolved in the artery enymatically. Angioplasty is the in which a balloon is used to push open the artery.

Great importance is placed on monitoring for various complications, that could prevent a secondy heart attack. Through this monitoring work is done to help eliminate any risk factors that may exist, which helps to reduce the odds of further heart attacks.

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Heart Attack Prevention Tips

While some have to fight the battle of the bulge for mere shallow reasons, there are those who do all the dieting and exercising to reduce their levels just to stay alive. And while is an important component of the membranes of cells, playing an important part in maintaining brain synapses as well as in the immune system, it is also the largest cause of attack and stroke.

While it is great that most people who are suffering from high levels of cholesterol go to their dieticians to have their daily eating habits tweaked by following a strict meal plan in order to help them lower their cholesterol levels (hopefully back to normal levels), some people have really gone overboard, but if you feel compelled to lower your cholestorol, consult with your doctor, most doctors are fine with prescribing cholesterol reducing .

When coupled with a healthy diet and regular exercise, the drugs can make quite a difference in your cholesterol levels, at least enough that your levels can be considered safe.

There are four kinds of cholesterol reducing drugs:

1. Bile acid

Sequesterants are cholesterol reducing drugs that aim to bind with the bile that is being produced by ones liver. The bile helps out in our digestion as well as in the absorption of fats from the intestine. This cholesterol reducing drug blocks out the digestion of fats from the bile to help prevent the formation of cholesterol. Various cholesterol reducing drugs in this category are the following:

- Colestipol
- Colestid
- Coleseyalam
- Welchol
- Cholestyramine
- Questran

2. Statins

Popularly known as statins, the HMG-CoA inhibitors are cholesterol reducing drugs that prevent the enzyme called 3-hydroxy-3-methyl-glutaryl-conenzyme, a reductase, from converting fat into cholesterol. This cholesterol reducing drug is seen as the most effective one in the market today and does some added good to ones body as 2003 reports claim that people with heart failure but no coronary artery diseases receive great benefits from this in as early as 14 weeks.

Popular drugs from this cholesterol reducing drug group include:

- Simvastatin
- Zocor
- Cerivastatin
- Baycol
- Fluvastatin
- Lescol
- Lovastatin
- Mevacor
- Prevastatin
- Pravachol
- Atorvastatin
- Lipitor

3. Fibric Acid

The cholesterol reducing drug called fibric acid and its derivaties are less effective than the statins when in comes to lowering ones cholesterol level.

Popular drugs under this kind of cholesterol reducing drugs are:

- Clofibrate
- Atormid-S
- Gemfibrozil
- Lopid
- Fenofribrate
- Tricor


Niacin, or vitamin B-3, also is effective in lowering cholesterol levels. Although the normal vitamin dose of niacin is only set at 20 mg for each day, the dose required to reduce cholesterol levels is at least 500 mg each day. Niacin helps reduce cholesterol by inhibiting very low density lipoprotein (VLDL) secretion in the bloodstream.

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Colon Treatment For Getting Rid Of Colon Cancer

is one of the major diseases that claim thousands of lives every year in the USA. The reason has been attributed to American peoples fetish for low fiber-high diet. Add to it the lack of physical movement and tensions of modern day living and you will see the reason why USA is one of the five countries where the occurrences of colon cancer are so common.

However, science is not sitting idle either and a number of sophisticated treatments are available to deal with the challenges of a bad colon that is the direct consequence of an unhealthy lifestyle. Of late three major types of treatments are most popular in the USA to deal with colon cancer. They are described below.

1. Surgical operation
When colon cancer is detected in an early stage, surgery proves to be extremely beneficial. In an early stage with the aid of a colonoscope, the cancerous cells are removed.

When the cancer is detected at an advanced stage, the surgical that is performed is called resection. It is a process of removing the tumor by making an incision in the abdomen. After the removal of the tumor the colon is stitched back to restore the continuity of the large intestine.

Chemotherapy is applied in cases of most advanced stages of colon cancer. Chemotherapy literally means killing of cancerous cells through chemical treatment. Two major chemicals that most physicians prefer to apply for the best result in colon cancer are fluorouracil (5-FU) and leucovorin.

3. Therapy
Most people get startled to hear that radiation is used to treat any disease, as we generally associated with such monstrous things as nuclear bombs. But truth of the matter is that, we are constantly being exposed to some kind of radiation from simple objects of mundane life like mobile phones and even most innocent looking radios. We have to absorb some amount of radiation even as a price for living in this earth. Although radiation is not good for our health but our system somehow copes up in dealing with this. The same is true for the cancer patients who are administered radiation as a therapeutic procedure. In case of colon cancer, patients receive radiation mainly before surgery to make the things easier for the surgeon, as radiation reduces the size of the tumor. After the operation has been performed, radiation is applied to ensure that the tumor doe not come back again. Radiation becomes the only means of treatment to destroy cancerous cells, when it is not possible to remove the tumor by the means of surgery

Usually, radiation is charged externally and each application takes little time to finishjust a few minutes per day. The patient has to undergo the radiation therapy five days a week and the total span of treatment may last for many weeks.

Barring some exceptions, colon cancer is actually the result of unhygienic life style and following the good old adage, prevention is better than cure, you can prevent this curse ruining your life. A little care for what you eat, simple exercises, little efforts to keep the stress at bay and of course a regular colon cleansing regimen can help you to enjoy life in its fullest.

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